Icd 10 code for chronic lymphocytic leukemia b cell type

Icd 10 code for chronic lymphocytic leukemia b cell type

Name

ICD-O-1 Morphology

Effective 1978 - 1991

ICD-O-2 Morphology

Effective 1992 - 2000

ICD-O-3 Morphology

Effective 2001 and later

Reportable

for cases diagnosed 1978 and later

Primary Site(s)

See Module 3: Rules PH5, PH6

Most common sites of involvement: bone marrow, peripheral blood, lymph nodes

Help me code for diagnosis year :

Abstractor Notes

Diagnostic Confirmation

This histology can be determined by positive histology (including peripheral blood) with or without genetics and/or immunophenotyping. Review the Definitive Diagnostic Methods, Immunophenotyping and Genetics Data sections below, and the instructions in the Hematopoietic Manual for further guidance on assigning Diagnostic confirmation.

Module Rule

Alternate Names

All variants of BCLL

CLL/SLL

SLL

SLL/CLL

Definition

Definitive Diagnostic Methods

FISH

Flow cytometry

Genetic testing

Histologic confirmation

Immunophenotyping

Genetics Data

Immunophenotyping

CD5+

CD10-

CD11c

CD19 expressed

CD20 expressed

CD22 expressed

CD23+

CD43+

CD79A

CD79b expressed

CD200+

Cyclin D1 not expressed

FMC7 negative or weakly expressed

LEF1 aberrantly expressed

Weak or dim surface IgM/IgD

Treatments

Chemotherapy

Hormone therapy

Immunotherapy

Transformations to

Transformations from

None

Same Primaries

Corresponding ICD-9 Codes

204.1 Chronic lymphoid leukemia (CLL)

Corresponding ICD-10 Codes

C91.1 Chronic lymphocytic leukemia (CLL)

Corresponding ICD-10-CM Codes (U.S. only)

C91.1 Chronic lymphocytic leukemia of B-cell type (CLL) (effective October 01, 2015)

Signs and Symptoms

Extranodal infiltrates

Fatigue

Hepatomegaly

Infections

Lymphadenopathy

Splenomegaly

Diagnostic Exams

Flow cytometry

Immunohistochemistry

Immunophenotyping

Progression and Transformation

2-8% of CLL patients transform to DLBCL

<1% of CLL patients develop classical Hodgkin lymphoma

Epidemiology and Mortality

Age: 65 years median age (diagnosis in younger adults increasing)

Incidence: 2-6 cases per 100,000 per person per year (most common leukemia in adults in Western countries)

Race: slight female predominance

Sources

Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J (Eds):
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues (Revised 4th edition)
IARC: Lyon 2017
Section: Mature B-cell neoplasms
Pages: 216-220

International Classification of Diseases for Oncology, Third Edition, Second Revision. Geneva: World Health Organization, 2020.
Section: ICD-O-3.2 (2020) Morphological Codes
Pages: http://www.iacr.com.fr/index.php?option=com_content&view=category&layout=blog&id=100&Itemid=577

National Cancer Institute
Section: General Information About Adult Non-Hodgkin Lymphoma (NHL)
Pages: https://www.cancer.gov/types/lymphoma/hp/adult-nhl-treatment-pdq

Icd 10 code for chronic lymphocytic leukemia b cell type

Leukemia, Lymphocytic, Chronic, B-Cell D015451

1 indication for 561 drugs (206 approved, 355 experimental)

Diseases [C] » Pathological Conditions, Signs and Symptoms [C23] » Pathologic Processes » Disease Attributes » Chronic Disease » Leukemia, Lymphocytic, Chronic, B-Cell

Diseases [C] » Neoplasms [C04] » Neoplasms by Histologic Type » Leukemia » Leukemia, Lymphoid » Leukemia, B-Cell » Leukemia, Lymphocytic, Chronic, B-Cell

Diseases [C] » Hemic and Lymphatic Diseases [C15] » Lymphatic Diseases » Lymphoproliferative Disorders » Leukemia, Lymphoid » Leukemia, B-Cell » Leukemia, Lymphocytic, Chronic, B-Cell

Diseases [C] » Immune System Diseases [C20] » Immunoproliferative Disorders » Lymphoproliferative Disorders » Leukemia, Lymphoid » Leukemia, B-Cell » Leukemia, Lymphocytic, Chronic, B-Cell

A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease.   MeSH

What is chronic lymphocytic leukemia of B

Chronic lymphocytic leukemia (CLL) is a malignancy of CD5+ B cells that is characterized by the accumulation of small, mature-appearing neoplastic lymphocytes in the blood, marrow, and secondary lymphoid tissues. Genetic factors contribute to the development of CLL.

What is the ICD 10 code for chronic lymphocytic leukemia?

ICD-10 code C91. 10 for Chronic lymphocytic leukemia of B-cell type not having achieved remission is a medical classification as listed by WHO under the range - Malignant neoplasms .

Is B

In CLL, the abnormal B cells build up in your blood and bone marrow. This is why it's called 'leukaemia' – after 'leucocytes': the medical name for white blood cells. In SLL, the abnormal B cells mainly build up in your lymph nodes. This is why it's called lymphoma'.

Does chronic lymphocytic leukemia affect B cells?

Chronic lymphocytic leukaemia (CLL) is a type of slow-growing leukaemia that affects developing B-lymphocytes. B lymphocytes (also known as B-cells) are specialised white blood cells.